What information do the breast and ovarian cancer models use to determine risks?
Table of Risk Factors
Risk Factor | Breast Cancer | Ovarian Cancer |
---|---|---|
Family and personal-proband history of breast, ovarian, prostate and pancreatic cancer | ||
Rare pathogenic variants in moderate and high risk susceptibility genes |
|
|
Age information on unaffected family members | ||
Ashkenazi Jewish origin | ||
Information on year of birth to capture birth cohort | ||
Age of menarche | ||
Parity | ||
Age at first live birth | ||
Use of oral contraception | ||
Use of menopause hormone therapy | ||
Body mass index | ||
Daily alcohol intake | ||
Mammographic density | ||
Height | ||
Tubal ligation procedure | ||
Endometriosis | ||
Common cancer genetic susceptibility variants |
- indicates used by cancer risk prediction model