What information do the breast, ovarian and prostate cancer models use to determine risks?
Table of Risk Factors
Risk Factor | Breast Cancer | Ovarian Cancer | Prostate Cancer |
|---|---|---|---|
Family and personal-proband history of breast, ovarian, prostate and pancreatic cancer |
| ||
Rare pathogenic variants in moderate and high risk susceptibility genes |
|
|
|
Age information on unaffected family members |
| ||
Ashkenazi Jewish origin |
| ||
Information on year of birth to capture birth cohort |
| ||
Age of menarche |
| ||
Parity |
| ||
Age at first live birth |
| ||
Use of oral contraception |
| ||
Use of menopause hormone therapy |
| ||
Body mass index |
| ||
Daily alcohol intake |
| ||
Mammographic density |
| ||
Height |
| ||
Tubal ligation procedure |
| ||
Endometriosis |
| ||
Common cancer genetic susceptibility variants |
|
- indicates used by cancer risk prediction model