/
How can I change the genetic test sensitivity?
How can I change the genetic test sensitivity?
- Tim Carver
- Alex Cunningham PhD (Unlicensed)
Owned by Tim Carver
Last updated: Nov 28, 2019 by Alex Cunningham PhD (Unlicensed)
In the CanRisk Tool, genetic test (mutation search) sensitivities are listed in the 'Family History' section under the 'Advanced Options' menu. You can change the genetic test sensitivity for each gene and each risk model (i.e. for the breast cancer (BOADICEA) model or the ovarian cancer model) by selecting the 'Use custom mutation sensitivities' checkbox at the bottom of the menu, and specifying your 'custom' genetic test sensitivity in the corresponding text field.
Also, note that the genetic test sensitivity values used in your risk calculation will be reported in the 'Inputs' tab in the 'Result' Web page once you have run your risk calculation .
, multiple selections available,
Related content
Can I specify default settings for the proband's country of residence and mutation search sensitivities?
Can I specify default settings for the proband's country of residence and mutation search sensitivities?
More like this
What is the difference between a mutation search and a direct gene test?
What is the difference between a mutation search and a direct gene test?
Read with this
How do I enter Polygenic Risk Scores manually using the CanRisk Tool?”
How do I enter Polygenic Risk Scores manually using the CanRisk Tool?”
More like this
Mutation carrier probabilities in families with members that have two or more mutations or families with mutations in more than one gene
Mutation carrier probabilities in families with members that have two or more mutations or families with mutations in more than one gene
More like this
Why do BRCA mutation carrier probabilities sometimes increase abruptly when I increase an age at breast cancer diagnosis from 19 to 20 years in my input pedigree?
Why do BRCA mutation carrier probabilities sometimes increase abruptly when I increase an age at breast cancer diagnosis from 19 to 20 years in my input pedigree?
More like this
How are rare genetic pathogenic variants in BRCA1, BRCA2, PALB2, ATM, CHEK2 , RAD51C, RAD51D, and BRIP1 used in the CanRisk Tool?
How are rare genetic pathogenic variants in BRCA1, BRCA2, PALB2, ATM, CHEK2 , RAD51C, RAD51D, and BRIP1 used in the CanRisk Tool?
More like this