In order for BOADICEA to calculate breast and ovarian cancer risks, the target (the index or subject of the calculation) must be either: (1) a female who is unaffected by cancer, or (2) a female who has developed one breast cancer only. As a result, cancer risks will not be computed if the target has developed other cancers, or the target is male.
Similarly, BOADICEA calculates breast and ovarian cancer risks for individuals with a maximum age of 80. Therefore, cancer risks will not be calculated if the age of the target of 80 years or greater.