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Why has the program calculated mutation carrier probabilities but not cancer risks?
Why has the program calculated mutation carrier probabilities but not cancer risks?
- Tim Carver
Owned by Tim Carver
Jan 17, 2020
In order for BOADICEA to calculate breast and ovarian cancer risks, the target (the index or subject of the calculation) must be either: (1) a female who is unaffected by cancer, or (2) a female who has developed one breast cancer only. As a result, cancer risks will not be computed if the target has developed other cancers, or the target is male.
Similarly, BOADICEA calculates breast and ovarian cancer risks for individuals with a maximum age of 80. Therefore, cancer risks will not be calculated if the age of the target of 80 years or greater.
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