Risk Calculations
- How do you define breast cancer?
- How do you define ovarian cancer?
- Are risk estimates sensitive to variations in the age at last follow up?
- How can I change the genetic test sensitivity?
- How are the units and grams of alcohol calculated?
- How can I avoid underestimating risks?
- What is the difference between a mutation search and a direct gene test?
- Why are 'Age or age at death' and 'Year of birth' vital to risk estimates?
- Should I estimate age at last follow up and year of birth if they are missing?
- If an age at last follow up is uncertain, can I run several calculations to see the effect of different ages?
- Why are the breast/ovarian cancer risks computed for the index lower than the equivalent population cancer risks in my cancer risk graphs?
- Is there an upper limit on the ages at cancer diagnosis considered by the CanRisk Tool?
- Can the CanRisk tool be used in cases of Ductal Carcinoma-In-Situ (DCIS)?
- Why has the program calculated mutation carrier probabilities but not cancer risks?
- What does the population risk refer to in the risk plots for contralateral breast cancer?
- What information do the breast and ovarian cancer models use to determine risks?
- How should contralateral breast cancer risk predictions be interpreted?
- Can contralateral breast cancer be included for male individuals in CanRisk?
- Is it possible to set the pathology for males with a first breast cancer?
- How were the default gene-specific genetic test sensitivities in the CanRisk Tool chosen?
- Can the CanRisk Tool be used to estimate breast cancer risks for both breasts after a patient has developed a first breast cancer?
- Why don't some CanRisk Tool results match results obtained with earlier versions of the CanRisk Tool or the BOADICEA Web Application?
- Why does the CanRisk Tool sometimes fail to process pedigrees with loops?
- What is the best approach in cases of Risk-Reducing Salpingo-Oophorectomy (RRSO)?