Spaces
Apps
Templates
Create
CanRisk Knowledgebase
All content
Space settings
Shortcuts
How-to articles
How-to articles
This trigger is hidden
Project task report blueprint
Project task report blueprint
This trigger is hidden
Content
Results will update as you type.
How-to articles
FAQ articles
About the CanRisk Tool
CanRisk Pedigree Data File Format
Polygenic Risk Score
Mutation Carrier Probabilities
Risk Calculations
•
How do you define breast cancer?
•
How do you define ovarian cancer?
•
Are risk estimates sensitive to variations in the age at last follow up?
•
How can I change the genetic test sensitivity?
•
How are the units and grams of alcohol calculated?
•
How can I avoid underestimating risks?
•
What is the difference between a mutation search and a direct gene test?
•
Why are 'Age or age at death' and 'Year of birth' vital to risk estimates?
•
Should I estimate age at last follow up and year of birth if they are missing?
•
If an age at last follow up is uncertain, can I run several calculations to see the effect of different ages?
•
Why are the breast/ovarian cancer risks computed for the index lower than the equivalent population cancer risks in my cancer risk graphs?
•
Is there an upper limit on the ages at cancer diagnosis considered by the CanRisk Tool?
•
Can the CanRisk tool be used in cases of Ductal Carcinoma-In-Situ (DCIS)?
•
Why has the program calculated mutation carrier probabilities but not cancer risks?
•
What does the population risk refer to in the risk plots for contralateral breast cancer?
•
What information do the breast and ovarian cancer models use to determine risks?
•
How should contralateral breast cancer risk predictions be interpreted?
•
Can contralateral breast cancer be included for male individuals in CanRisk?
•
Is it possible to set the pathology for males with a first breast cancer?
•
How were the default gene-specific genetic test sensitivities in the CanRisk Tool chosen?
•
Can the CanRisk Tool be used to estimate breast cancer risks for both breasts after a patient has developed a first breast cancer?
•
Why don't some CanRisk Tool results match results obtained with earlier versions of the CanRisk Tool or the BOADICEA Web Application?
•
Why does the CanRisk Tool sometimes fail to process pedigrees with loops?
•
What is the best approach in cases of Risk-Reducing Salpingo-Oophorectomy (RRSO)?
Risk Results
Input pedigree/family history data
•
CanRisk v2.4.0 - updated BRCA2 relative risks
User Documentation
Web-Services
Troubleshooting articles
•
Project task report blueprint
Apps
Gliffy Diagram
CanRisk Knowledgebase
/
/
Risk Calculations
/
How do you define breast cancer?
Summarize
How do you define breast cancer?
Tim Carver
Alex Cunningham PhD (Unlicensed)
Owned by
Tim Carver
Last updated:
May 28, 2020
by
Alex Cunningham PhD (Unlicensed)
1 min read
Loading data...
Breast cancer is taken to mean invasive breast cancer. Ductal carcinoma-in-situ (DCIS) should
not
be included in CanRisk Tool risk calculations as the program was not developed for in-situ cancers.
{"serverDuration": 41, "requestCorrelationId": "5a4c8a4e711845c585e46320a8740d07"}