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Can the CanRisk Tool calculate mutation carrier probabilities for known mutation carriers?
Can the CanRisk Tool calculate mutation carrier probabilities for known mutation carriers?
No, if the target (index or subject of the risk calculation) has had a positive genetic test, the CanRisk Tool cannot calculate mutation carrier probabilities for that individual.
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Why has the CanRisk Tool calculated mutation carrier probabilities but not cancer risks?
Why has the CanRisk Tool calculated mutation carrier probabilities but not cancer risks?
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Why does the CanRisk Tool predict a high residual mutation carrier probability when the target has had a negative mutation search?
Why does the CanRisk Tool predict a high residual mutation carrier probability when the target has had a negative mutation search?
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When calculating mutation carrier probabilities, which input data/parameters most strongly influence the resulting probabilities?
When calculating mutation carrier probabilities, which input data/parameters most strongly influence the resulting probabilities?
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Mutation carrier probabilities in families with members that have two or more mutations or families with mutations in more than one gene
Mutation carrier probabilities in families with members that have two or more mutations or families with mutations in more than one gene
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Can the CanRisk Tool estimate risks for Ashkenazi Jewish individuals?
Can the CanRisk Tool estimate risks for Ashkenazi Jewish individuals?
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How were the default gene-specific genetic test sensitivities in the CanRisk Tool chosen?
How were the default gene-specific genetic test sensitivities in the CanRisk Tool chosen?
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