Can I specify default settings for the proband's country of residence and mutation search sensitivities?

Yes, you can specify a default country of residence for the proband in the User Preferences menu (select the Preferences button at the top of the CanRisk Tool web page to open this menu). For example, if you specify “Sweden” in the User Preferences menu, breast/ovarian cancer risks will then be computed using Swedish cancer incidence rates. And when you log back into the CanRisk Tool at a later date, the proband’s country of residence will automatically be set to “Sweden“ by default.

You can also specify default mutation search sensitivities for the high and intermediate risk genes (BRCA1, BRCA2 and others) in the User Preferences menu. And when you log back into the CanRisk Tool at a later date, these mutation search sensitivities will also be set by default.

Please note that User Preferences settings are saved in the browser storage on your own computer. And so if you wish to use the CanRisk Tool on a different computer at a later date, you will need to set them again on that machine.