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As the lifestyle/hormonal risk factors are associated with the target it is not possible to change the target on-the-fly. It is necessary to use the 'Reset' button to change the target which clears the risk factors and pedigree. Before using the 'Reset' it is worth considering saving the CanRisk file, to be able to re-load the current target. The issue of changing the target and maintaining the pedigree information will be addressed in future versions of the CanRisk tool.