As
the lifestyle/hormonal risk factors are associated with the target (index or subject of the risk calculation), it is not possible to change the target on-the-fly.
It is necessary change the target which clears the Before Reset' it is worth considering saving the CanRisk file, to be able to re-load the current target. The issue of changing the target and maintaining the pedigree information will be addressed in future versions of the CanRisk
toolTool.