The following information is used to determine risks:
The familyTable of Risk Factors
Risk Factor | Breast Cancer | Ovarian Cancer |
---|---|---|
Family history of breast, ovarian, prostate and pancreatic cancer | ||
Rare pathogenic variants in moderate and high risk susceptibility genes |
|
BRCA1, BRCA2, RAD51D, RAD51C, BRIP1 |
Age information on unaffected family members | ||
Ashkenazi Jewish origin | ||
Information on year of birth to capture birth cohort |
The following risk factors are used:
Age |
of |
menarche | ||
Parity | ||
Age |
at |
first |
live |
birth | ||
Use |
of |
oral |
contraception | ||
Use |
of |
menopause |
hormone |
therapy | ||
Body |
mass |
index | ||
Daily |
alcohol |
intake | ||
Mammographic |
density | ||
Height | ||
Tubal |
ligation |
procedure | ||
Endometriosis | ||
Common |
cancer |
genetic |
susceptibility |
variants |
Risk |
Scores) |
- indicates used by cancer risk prediction model